The vast pool of structurally and functionally distinct secondary metabolites (i.e., natural products (NPs)) is constantly being expanded, a process also driven by the rapid progress in the development of analytical techniques.Such NPs often show potent biological activities and are therefore prime candidates for drug development and medical applic
Capacity Analysis of Channel Inversion Using Space-Time Block Coding with Transmit Power Control
In this paper, we analyze channel inversion with transmit diversity in terms of capacity and bit error rates in correlated fading.We obtain the Shannon here capacity of Rayleigh fading channel under channel inversion using spatially correlated dual branch orthogonal space-time block coding, in comparison with the optimal power and rate adaptation p
Effects of stress or infection on rat behavior show robust reversals due to environmental disturbance [version 2; referees: 2 approved]
Background: The behavior of animals is intricately linked to the environment; a relationship that is often studied in laboratory conditions by using environmental perturbations to study biological mechanisms underlying the behavioral change.Methods: This study pertains to two such well-studied and well-replicated perturbations, i.e., stress-induced
FAK inhibition alone or in combination with adjuvant therapies reduces cancer stem cell activity
Abstract Cancer stem-like cells (CSC) contribute to therapy resistance and recurrence.Focal adhesion kinase (FAK) has a role in CSC regulation.We determined the effect of FAK inhibition on breast CSC activity alone and in combination with adjuvant therapies.FAK inhibition reduced CSC activity ngetikin and self-renewal across all molecular subtypes